Pigmented Purpuric Dermatoses
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چکیده
The aetiology is unknown but important contributory factors include venous hypertension, exercise and gravitational dependency [2] . Histology shows a perivascular lymphocytic infiltrate of T cells centred on the superficial small blood vessels of the skin, suggesting that cell-mediated immunity plays a part [3] . There is swelling of endothelial cells and narrowing of the lumen. Extravasation of red blood cells occurs with marked deposition of haemosiderin in macrophages, and a rare granulomatous variant of chronic pigmented dermatosis has been reported.
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Pentoxifylline in the treatment of pigmented purpuric dermatoses: A randomized, controlled trial
Background and aim: Pigmented purpuric dermatoses are a group of chronic and recurrent skin diseases resulting from lymphocyte-mediated leakage of erythrocytes. No effective treatment has been suggested for these conditions. This study was performed to evaluate the efficacy of oral pentoxiphylline in the treatment of pigmented purpuric dermatoses.Materials and Methods: ...
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